Scalable lentiviral screening of variants associated with kidney disease

Project: Research

Project Details

Project Description

This proposal seeks to extend an established high-throughput, functional genomics platform to characterise multiple genetic variants of uncertain clinical significance in the COL4A4 and HNF1A genes using in vitro models of the human kidney.
StatusActive
Effective start/end date1/03/25 → 30/09/26

Keywords

  • Stem Cells
  • Kidney organoids
  • Renal genetics
  • VUS
  • HNF4A
  • COL4A4