RNA-mediated regulation of the histone methyltransferase PRC2: a new link to disease-associated and causing mutations

Davidovich, Chen (Primary Chief Investigator (PCI))

Project: Research

Status	Finished
Effective start/end date	1/01/19 → 31/12/21

3 Article
2 Review Article

Allosteric regulation of histone lysine methyltransferases: From context-specific regulation to selective drugs
Davidovich, C. & Zhang, Q., Apr 2021, In: Biochemical Society Transactions. 49, 2, p. 591-607 17 p.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access

3 Citations (Scopus)
Not just a writer: PRC2 as a chromatin reader
Uckelmann, M. & Davidovich, C., Jun 2021, In: Biochemical Society Transactions. 49, 3, p. 1159-1170 12 p.
Research output: Contribution to journal › Review Article › Other › peer-review

Open Access

3 Citations (Scopus)
PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis
Zhang, Q., Agius, S. C., Flanigan, S. F., Uckelmann, M., Levina, V., Owen, B. M. & Davidovich, C., Dec 2021, In: Nature Communications. 12, 1, 18 p., 4592.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Citations (Scopus)

Centre for Electron Microscopy (MCEM)
Peter Miller (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
FlowCore
Andrew Fryga (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
MASSIVE
Paul Bonnington (Manager) & Slava Kitaeff (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility