The breakdown of fats in adipose tissue is termed lipolysis. Fats are the main energy source for whole body energy metabolism. Several novel proteins were recently discovered and are essential for lipolysis. We aim to determine how one of these proteins, comparative gene identification 58, is regulated and to assess its involvement for the maintenance of fat stores. Understanding lipolysis may enable the development of new processes in the food industry and the identification of novel therapeutic targets for the treatment of obesity related disorders such type 2 diabetes.