Reducing the impact of brain trauma by minimising glial scar formation through focal therapeutic protein delivery from an implantable depot.

Bourne, James (Primary Chief Investigator (PCI))
Teo, Leon (Chief Investigator (CI))

Australian Regenerative Medicine Institute

Project: Research

Project Description

Joint CSIRO and FMNHS Grant

Status	Finished
Effective start/end date	1/10/19 → 31/12/21

Keywords

biomaterial
neuroprotection

2 Article

TGFβ3, dibutyryl cAMP and a notch inhibitor modulate phenotype late in stem cell-derived dopaminergic neuron maturation
Sibuea, S., Ho, J. K., Pouton, C. W. & Haynes, J. M., 1 Feb 2023, In: Frontiers in Cell and Developmental Biology. 11, 13 p., 1111705.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease
Haynes, J. M., Sibuea, S. M., Aguiar, A. A., Li, F., Ho, J. K. & Pouton, C. W., 23 Dec 2021, In: PLoS ONE. 16, 12 December, 22 p., e0261730.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)

Animal Research Platform (MARP)
Christine Findlay (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Biomedical Imaging (MBI)
Kylie Reid (Manager), Robert Brkljaca (Manager), Christoph Hagemeyer (Other) & David Wright (Other)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
Micromon
Scott Coutts (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility