PhD Project: Altered Vitamin D responsiveness in Multiple Sclerosis Immune Cells.

This project will explore the hypothesis that people with Multiple Sclerosis (MS) have an altered immune cell response to Vitamin D compared to healthy individuals. Preliminary data from our group suggests that the relationship between endogenous Vitamin D serum level and expression of many RNA species is different between MS and HC, sometimes even inverted. This project may create new fundamental knowledge to understand the immune cascade of MS pathogenesis.