Project Details
Project Description
Peptide nucleic acids (PNAs) are analogues of DNA that may have important implications as therapeutic agents for the cure of diseases based on genetic defects. The attributes of PNAs that make them potentially viable as a drug are also well suited to their development as sensors and molecular devices. In this proposal, we wish to develop a series of PNAs containing photoactive elements (a) as alternatives to commercially-available fluorophores, (b) for the early detection of neurodegenerative diseases and (c) to contribute to one of Science's most debated issues i.e. ''does DNA mediate electron transport?''
Status | Finished |
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Effective start/end date | 1/01/03 → 31/12/05 |
Funding
- Australian Research Council (ARC): A$285,000.00
- Monash University