Peptide Nucleic Acid Based Sensors and Devices - An Investigation into PNA Versatility for Emerging Gene Technologies

  • Langford, Steven (Primary Chief Investigator (PCI))
  • Cheema, Surindar (Chief Investigator (CI))

Project: Research

Project Details

Project Description

Peptide nucleic acids (PNAs) are analogues of DNA that may have important implications as therapeutic agents for the cure of diseases based on genetic defects. The attributes of PNAs that make them potentially viable as a drug are also well suited to their development as sensors and molecular devices. In this proposal, we wish to develop a series of PNAs containing photoactive elements (a) as alternatives to commercially-available fluorophores, (b) for the early detection of neurodegenerative diseases and (c) to contribute to one of Science's most debated issues i.e. ''does DNA mediate electron transport?''
StatusFinished
Effective start/end date1/01/0331/12/05

Funding

  • Australian Research Council (ARC): AUD285,000.00
  • Monash University
  • Monash University