Optimisation by Platform Trial Involving Multiple Interventions with Simultaneous Evaluation in Community Acquired Pneumonia (OPTIMISE-CAP)

Webb, Steven (Primary Chief Investigator (PCI))
Berry, Donald (Chief Investigator (CI))
Cheng, Allen (Chief Investigator (CI))
Heritier, Stephane (Chief Investigator (CI))
Litton, Edward (Chief Investigator (CI))
McArthur, Colin (Chief Investigator (CI))
Paterson, David (Chief Investigator (CI))
Presneill, Jeffrey (Chief Investigator (CI))

Project: Research

Status	Active
Effective start/end date	1/01/16 → 31/12/22

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$4,413,145.20

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7 Article

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial
REMAP-CAP Writing Committee for the REMAP-CAP Investigators, Mar 2022, In: JAMA. 327, 13, p. 1247-1259 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

22 Citations (Scopus)
Interleukin-6 receptor antagonists in critically ill patients with covid-19
The REMAP-CAP Investigators, 22 Apr 2021, In: The New England Journal of Medicine. 384, 16, p. 1491-1502 12 p.
Research output: Contribution to journal › Article › Research › peer-review

740 Citations (Scopus)
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial
Arabi, Y. M., Gordon, A., Derde, L., Nichol, A. D., Murthy, S., Al-Beidh, F., Annane, D., Swaidan, L. A., Beane, A., Beasley, R., Berry, L. R., Bhimani, Z., Bonten, M., Bradbury, C., Brunkhorst, F., Buxton, M., Buzgau, A., Cheng, A., de Jong, M., Detry, M. A., & 48 othersDuffy, E., Estcourt, L., Fitzgerald, M., Fowler, R., Girard, T., Goligher, E., Goossens, H., Haniffa, R., Higgins, A. M., Hills, T. E., Horvat, C., Huang, D. T., King, A. J., Lamontagne, F., Lawler, P., Lewis, R., Linstrum, K., Litton, E., Lorenzi, E., Malakouti, S., McAuley, D., McGlothlin, A., McGuinness, S., McVerry, B. J., Montgomery, S. K., Morpeth, S. C., Mouncey, P., Orr, K., Parke, R., Parker, J. C., Patanwala, A. E., Rowan, K., Santos, M. S., Saunders, C. T., Seymour, C., Shankar-Hari, M., Tong, S. Y. C., Turgeon, A., Turner, A. M., Van de Veerdonk, F. L., Zarychanski, R., Green, C., Berry, S., Marshall, J. C., McArthur, C., Angus, D., Webb, S. A. & on behalf of the REMAP-CAP Investigators, Aug 2021, In: Intensive Care Medicine. 47, 8, p. 867-886 20 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

29 Citations (Scopus)

HELIX - Data Platform
Vivianne Andreou (Other), Mark Lucas (Other) & Andrew Runting (Other)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

Optimisation by Platform Trial Involving Multiple Interventions with Simultaneous Evaluation in Community Acquired Pneumonia (OPTIMISE-CAP)

Project Details

Funding

Research output

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial

Interleukin-6 receptor antagonists in critically ill patients with covid-19

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

Equipment

HELIX - Data Platform