Opiate-induced constipation: identifying key targets for therapy

Poole, Daniel (Primary Chief Investigator (PCI))
Canals, Meritxell, (Chief Investigator (CI))

Drug Discovery Biology

Project: Research

Status	Finished
Effective start/end date	1/01/13 → 31/12/15

Funding

National Health & Medical Research Council (NHMRC): AUD198,210.78
National Health & Medical Research Council (NHMRC): AUD198,210.81

Related content

Research Output

G protein-coupled receptor trafficking and signalling in the enteric nervous system: the past, present and future

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

Inflammation-associated changes in DOR expression and function in the mouse colon

Research output: Contribution to journal › Article › Research › peer-review

Clathrin and GRK2/3 inhibitors block δ-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon

Research output: Contribution to journal › Article › Research › peer-review

Distribution and trafficking of the μ-opioid receptor in enteric neurons of the guinea pig

Research output: Contribution to journal › Article › Research › peer-review

Agonist-dependent development of delta opioid receptor tolerance in the colon

Research output: Contribution to journal › Article › Research › peer-review

Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system

Research output: Contribution to journal › Article › Research › peer-review

Biological redundancy of endogenous GPCR ligands in the gut and the potential for endogenous functional selectivity

Research output: Contribution to journal › Article › Research › peer-review