Opiate-induced constipation: identifying key targets for therapy

Project: Research

Status	Finished
Effective start/end date	1/01/13 → 31/12/15

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain
Jiménez-Vargas, N. N., Gong, J., Wisdom, M. J., Jensen, D. D., Latorre, R., Hegron, A., Teng, S. L., Di Cello, J., Rajasekhar, P., Veldhuis, N. A., Carbone, S., Yu, Y., Lopez, C. L., Polanco, J. J., Canals, M., Reed, D., Lomax, A. E., Schmidt, B. L., Leong, K. W., Vanner, S. & 3 others, Halls, M. L., Bunnett, N. & Poole, D. P., 30 Jun 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 15281-15292 12 p.
Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)
Inflammation without pain: Immune-derived opioids hold the key
Carbone, S. & Poole, D. P., 1 Feb 2020, In: Neurogastroenterology & Motility. 32, 2, 5 p., e13787.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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3 Citations (Scopus)
Agonist-dependent development of delta opioid receptor tolerance in the colon
DiCello, J. J., Saito, A., Rajasekhar, P., Sebastian, B. W., McQuade, R. M., Gondin, A. B., Veldhuis, N. A., Canals, M., Carbone, S. E. & Poole, D. P., Aug 2019, In: Cellular and Molecular Life Sciences. 76, 15, p. 3033–3050 18 p.
Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Project Details