Novel targets from the antibiotic resistance network in multi-drug resistant Helicobacter pylori

McDonald, Mike (Primary Chief Investigator (PCI))
Kwok-Schuelein, Terry (Chief Investigator (CI))

Project: Research

Status	Active
Effective start/end date	1/01/20 → 31/12/22

Keywords

antibiotic resistance
mutation screening
genetic association
molecular evolution
evolution

3 Article

Polymyxin dose tunes the evolutionary dynamics of resistance in multidrug-resistant Acinetobacter baumannii
Zhao, J., Zhu, Y., Lin, Y. W., Yu, H., Wickremasinghe, H., Han, J., Velkov, T., McDonald, M. J. & Li, J., Jul 2022, In: Clinical Microbiology and Infection. 28, 7, p. 1026.e1-1026.e5 5 p.
Research output: Contribution to journal › Article › Research › peer-review
Recombination resolves the cost of horizontal gene transfer in experimental populations of Helicobacter pylori
Nguyen, A. N. T., Woods, L. C., Gorrell, R., Ramanan, S., Kwok, T. & McDonald, M. J., 22 Mar 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 12, 10 p., e2119010119.
Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)
Horizontal gene transfer potentiates adaptation by reducing selective constraints on the spread of genetic variation
Woods, L. C., Gorrell, R. J., Taylor, F., Connallon, T., Kwok, T. & McDonald, M. J., 27 Oct 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 43, p. 26868-26875 8 p.
Research output: Contribution to journal › Article › Research › peer-review

12 Citations (Scopus)