Novel NOX5 inhibitors in diabetic nephropathy

Project: Research

Project Details

Project Description

The Department of Diabetes is interested in developing a new Nox inhibitor targeting the unique enzyme Nox5 which is an ideal target for diabetic complications including kidney disease. Preclinical studies will be initially be performed using 2 different ways to inhibit the enzyme Nox 5 (a pharmacological approach with a Nox5 inhibitor from Uni Geneva and a molecular approach using an antisense oligonucleotide approach)
Effective start/end date1/07/2131/12/21