Novel inhalation formulation of colistin and combination therapy against Gram-negative 'superbugs'.

Research output

Research output per year 2015 2015 2016 2017 2018 2018

• 8 Article

Research output per year

Research output per year

Search results

• 2018

  Elucidating the pharmacokinetics/pharmacodynamics of aerosolized colistin against multidrug-resistant acinetobacter baumannii and klebsiella pneumoniae in a mouse lung infection model

  Lin, Y-W., Zhou, Q. T., Han, M-L., Chen, K., Onufrak, N. J., Wang, J., Turnidge, J. D., Howden, B. P., Forrest, A., Chan, H. K. & Li, J., 1 Feb 2018, In: Antimicrobial Agents and Chemotherapy. 62, 2, 9 p., e01790.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

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  14 Citations (Scopus)

• Mechanism-based pharmacokinetic/pharmacodynamic modeling of aerosolized colistin in a mouse lung infection model

  Lin, Y-W., Zhou, Q. T., Han, M-L., Onufrak, N. J., Chen, K., Wang, J., Forrest, A., Chan, H-K. & Li, J., 1 Mar 2018, In: Antimicrobial Agents and Chemotherapy. 62, 3, 14 p., e01965-17.

  Research output: Contribution to journal › Article › Research › peer-review
  15 Citations (Scopus)
• 2017

  Aerosolized polymyxin B for treatment of respiratory tract infections: Determination of pharmacokinetic-pharmacodynamic indices for aerosolized polymyxin B against Pseudomonas aeruginosa in a mouse lung infection model

  Lin, Y. W., Zhou, Q., Onufrak, N. J., Wirth, V., Chen, K., Wang, J., Forrest, A., Chan, H-K. & Li, J., 1 Aug 2017, In: Antimicrobial Agents and Chemotherapy. 61, 8, 15 p., e00211-17.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  49 Citations (Scopus)

• Pulmonary Pharmacokinetics of colistin following administration of dry powder aerosols in rats

  Lin, Y. W., Zhou, Q. T., Hu, Y., Onufrak, N. J., Sun, S., Wang, J., Forrest, A., Chan, H. K. & Li, J., 1 Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 12 p., e00973.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)
• 2016

  Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin

  Wang, W., Zhou, Q. T., Sun, S-P., Denman, J. A., Gengenbach, T. R., Barraud, N., Rice, S. A., Li, J., Yang, M. & Chan, H-K., 1 Mar 2016, In: The AAPS Journal. 18, 2, p. 372-384 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  42 Citations (Scopus)

• How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder?

  Zhou, Q., Loh, Z. H., Yu, J., Sun, S. P., Gengenbach, T. R., Denman, J. A., Li, J. & Chan, H. K., 1 Sept 2016, In: The AAPS Journal. 18, 5, p. 1213-1224 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  46 Citations (Scopus)
• 2015

  Inhaled anti-infective chemotherapy for respiratory tract infections: successes, challenges and the road ahead

  Velkov, T., Abdul Rahim, N., Zhou, Q. T., Chan, H-K. & Li, J., 2015, In: Advanced Drug Delivery Reviews. 85, p. 65 - 82 18 p.

  Research output: Contribution to journal › Article › Research › peer-review
  78 Citations (Scopus)

• Powder production and particle engineering for dry powder inhaler formulations

  Lin, Y-W., Wong, J., Qu, L., Chan, H-K. & Zhou, Q., 2015, In: Current Pharmaceutical Design. 21, 27, p. 3902-3916 15 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  77 Citations (Scopus)