Novel inhalation formulation of bacteriophages against ‘superbugs’ causing respiratory infections

  • Chan, Hak-Kim (Primary Chief Investigator (PCI))
  • McLachlan, Andrew (Chief Investigator (CI))
  • Morgan, Kaye (Chief Investigator (CI))
  • Morales, Sandra (Chief Investigator (CI))

Project: Research

Project Description

Antimicrobial drug resistance is a major concern for human health that is not being addressed by
current strategies in the development of antimicrobial agents. Bacteriophages represent a unique
and innovative solution with significant therapeutic potential to manage serious infection with
resistant bacteria. The major limitation is how to effectively and efficiently deliver bacteriophages
to the site of serious infection. This research will for the first time develop and evaluate a novel
formulation to deliver bacteriophages to the respiratory tract, providing proof of principle for
this innovative approach to treating serious life threatening infections which would represent a
major advance in overcoming a major unmet urgent medical need.

StatusActive
Effective start/end date2/01/181/01/21

Funding

  • National Health & Medical Research Council (NHMRC): AUD563,620.90