Novel combination therapies targeting the ribosome to treat prostate cancer

Furic, Luc (Primary Chief Investigator (PCI))
Daly, Roger (Chief Investigator (CI))
Hannan, Ross (Chief Investigator (CI))
Risbridger, Gail (Chief Investigator (CI))
Pearson, Richard D. (Partner Investigator (PI))
Sandhu, Shahneen K. (Partner Investigator (PI))

Project: Research

Status	Finished
Effective start/end date	1/05/15 → 30/04/18

Funding

Cancer Australia: A$255,000.00

2 Article
1 Review Article

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy
Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S. & Hedwards, S. & 32 others, Huglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., Nov 2018, In: European Urology. 74, 5, p. 562-572 11 p.
Research output: Contribution to journal › Article › Research › peer-review

92 Citations (Scopus)
mTOR-sensitive translation: Cleared fog reveals more trees
Masvidal, L., Hulea, L., Furic, L., Topisirovic, I. & Larsson, O., 3 Oct 2017, In: RNA Biology. 14, 10, p. 1299-1305 7 p.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access
File

56 Citations (Scopus)
Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription
Kang, J., Kusnadi, E. P., Ogden, A. J., Hicks, R. J., Bammert, L., Kutay, U., Hung, S., Sanij, E., Hannan, R. D., Hannan, K. M. & Pearson, R. B., 2016, In: Oncotarget. 7, 31, p. 48887-48904 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

8 Citations (Scopus)

Novel combination therapies targeting the ribosome to treat prostate cancer

Project Details

Funding

Research output

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

mTOR-sensitive translation: Cleared fog reveals more trees

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription