Novel approaches to prediction of caspase cleavage sites

In this project, we aim to develop next-generation methods for improved prediction of caspase target substrates and cleavage sites. For that purpose, we will perform an in-depth analysis of all existing tools and identify their advantages and disadvantages. Based on our benchmarking analysis, we will further develop novel accurate prediction methods. We will leverage several public databases (available in Genome Net and KEGG knowledgebase) developed by ICR, Kyoto University. We will also use high performance computer systems (including the super computer system) available in the ICR, Kyoto University.