Novel Antimicrobial and Anti-Leishmanial Bismuth Compounds and Materials

  • Andrews, Philip (Primary Chief Investigator (PCI))
  • Kedzierski, Lukasz, (Chief Investigator (CI))
  • Mehring, Michael (Partner Investigator (PI))
  • Sun, Hongzhe (Partner Investigator (PI))

Project: Research

Project Description

The project aims to establish advances in the fundamental bioinorganic and medicinal chemistry of bismuth and related metals, with relevance to two urgent and significant major global health issues; parasitic infections, principally Leishmaniasis, and antibacterial resistance. Through targeting serious microbial infections, the project aims to deepen knowledge of the chemical, physical, structural and biological properties of bismuth and related metals. The aim is to form bio-protective materials and surfaces through incorporation of bismuth, and its compounds, into polymer matrices. The chemical biology and toxicology of the complexes will be established through scrutiny of cellular mechanisms, particularly modern metallomic techniques.
StatusActive
Effective start/end date1/03/1731/12/19

Funding

  • Australian Research Council (ARC): AUD372,500.00
  • Australian Research Council (ARC)
  • Monash University: AUD349,353.00
  • University of Hong Kong: AUD116,268.00
  • Technische Universitat Chemnitz (Chemnitz University of Technology): AUD185,175.00