NHMRC Research Fellowship

Research output

Research output per year 2014 2017 2018 2019 2020 2021 2022 2022

• 26 Article
• 5 Review Article
• 1 Chapter (Book)

Research output per year

Research output per year

Search results

• 2022

  Neuroendocrine cells in prostate cancer correlate with poor outcomes: a systematic review and meta-analysis

  Kannan, A., Clouston, D., Frydenberg, M., Ilic, D., Karim, M. N., Evans, S. M., Toivanen, R., Risbridger, G. P. & Taylor, R. A., Oct 2022, In: BJU International. 130, 4, p. 420-433 14 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  5 Citations (Scopus)

• OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer

  Obinata, D., Funakoshi, D., Takayama, K., Hara, M., Niranjan, B., Teng, L., Lawrence, M. G., Taylor, R. A., Risbridger, G. P., Suzuki, Y., Takahashi, S. & Inoue, S., Dec 2022, In: Scientific Reports. 12, 1, 13 p., 6094.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer

  Alizadeh-Ghodsi, M., Owen, K. L., Townley, S. L., Zanker, D., Rollin, S. P. G., Hanson, A. R., Shrestha, R., Toubia, J., Gargett, T., Chernukhin, I., Luu, J., Cowley, K. J., Clark, A., Carroll, J. S., Simpson, K. J., Winter, J. M., Lawrence, M. G., Butler, L. M., Risbridger, G. P., Thierry, B., & 5 othersTaylor, R. A., Hickey, T. E., Parker, B. S., Tilley, W. D. & Selth, L. A., Jul 2022, In: Cancer Research Communications. 2, 7, p. 706-724 19 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
• 2021

  Androgen receptor enhancer amplification in matched patient-derived xenografts of primary and castrate-resistant prostate cancer

  Porter, L. H., Bakshi, A., Pook, D., Clark, A., Clouston, D., Kourambas, J., MURAL investigators, Goode, D. L., Risbridger, G. P., Taylor, R. A. & Lawrence, M. G., Jun 2021, In: Journal of Pathology. 254, 2, p. 121-134 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  11 Citations (Scopus)

• CX-5461 sensitizes DNA damage repair-proficient castrate-resistant prostate cancer to PARP inhibition

  Lawrence, M. G., Porter, L. H., Choo, N., Pook, D., Grummet, J. P., Pezaro, C. J., Sandhu, S., Ramm, S., Luu, J., Bakshi, A., Goode, D. L., Sanij, E., Pearson, R. B., Hannan, R. D., Simpson, K. J., Taylor, R. A., Risbridger, G. P. & Furic, L., Nov 2021, In: Molecular Cancer Therapeutics. 20, 11, p. 2140-2150 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  7 Citations (Scopus)

• High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

  Choo, N., Ramm, S., Luu, J., Winter, J. M., Selth, L. A., Dwyer, A. R., Frydenberg, M., Grummet, J., Sandhu, S., Hickey, T. E., Tilley, W. D., Taylor, R. A., Risbridger, G. P., Lawrence, M. G. & Simpson, K. J., Oct 2021, In: SLAS Discovery. 26, 9, p. 1107-1124 18 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  23 Citations (Scopus)

• Mast cell‐derived samd14 is a novel regulator of the human prostate tumor microenvironment

  Teng, L. K. H., Pereira, B. A., Keerthikumar, S., Huang, C., Niranjan, B., Lee, S. N., Richards, M., Schittenhelm, R. B., Furic, L., Goode, D. L., Lawrence, M. G., Taylor, R. A., Ellem, S. J., Risbridger, G. P. & Lister, N. L., 2 Mar 2021, In: Cancers. 13, 6, 23 p., 1237.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  8 Citations (Scopus)

• Oxytocin receptor antagonists as a novel pharmacological agent for reducing smooth muscle tone in the human prostate

  Lee, S. N., Kraska, J., Papargiris, M., Teng, L., Niranjan, B., Hammar, J., Ryan, A., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Ellem, S. J., Whittaker, M., Risbridger, G. P. & Exintaris, B., Dec 2021, In: Scientific Reports. 11, 1, 11 p., 6352.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

• The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

  Risbridger, G. P., Clark, A. K., Porter, L. H., Toivanen, R., Bakshi, A., Lister, N. L., Pook, D., Pezaro, C. J., Sandhu, S., Keerthikumar, S., Quezada Urban, R., Papargiris, M., Kraska, J., Madsen, H. B., Wang, H., Richards, M. G., Niranjan, B., O’Dea, S., Teng, L., Wheelahan, W., & 25 othersLi, Z., Choo, N., Ouyang, J. F., Thorne, H., Devereux, L., Hicks, R. J., Sengupta, S., Harewood, L., Iddawala, M., Azad, A. A., Goad, J., Grummet, J., Kourambas, J., Kwan, E. M., Moon, D., Murphy, D. G., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Furic, L., Goode, D. L., Frydenberg, M., Lawrence, M. G. & Taylor, R. A., 19 Aug 2021, In: Nature Communications. 12, 1, 5049.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  26 Citations (Scopus)
• 2020

  Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

  Lawrence, M. G., Pidsley, R., Niranjan, B., Papargiris, M., Pereira, B. A., Richards, M., Teng, L., Norden, S., Ryan, A., Frydenberg, M., Stirzaker, C., Taylor, R. A., Risbridger, G. P. & Clark, S. J., 18 Mar 2020, In: Clinical Epigenetics. 12, 1, 18 p., 48.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

• Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

  Jaeschke, A., Jacobi, A., Lawrence, M. G., Risbridger, G. P., Frydenberg, M., Williams, E. D., Vela, I., Hutmacher, D. W., Bray, L. J. & Taubenberger, A., Sept 2020, In: Materials Today Bio. 8, 14 p., 100073.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

• Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

  Lam, D., Luu, P. L., Song, J. Z., Qu, W., Risbridger, G. P., Lawrence, M. G., Lu, J., Trau, M., Korbie, D., Clark, S. J., Pidsley, R. & Stirzaker, C., 22 Jun 2020, In: Clinical Epigenetics. 12, 1, 16 p., 90.

  Research output: Contribution to journal › Article › Other › peer-review

  Open Access

  File
  15 Citations (Scopus)

• PDX: Moving beyond drug screening to versatile models for research discovery

  Risbridger, G., Lawrence, M. & Taylor, R. A., 1 Nov 2020, In: Journal of the Endocrine Society. 4, 11, 9 p., bvaa132.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)

• Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer

  Obinata, D., Lawrence, M. G., Takayama, K., Choo, N., Risbridger, G. P., Takahashi, S. & Inoue, S., 8 Oct 2020, In: Frontiers in Oncology. 10, 11 p., 581515.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  22 Citations (Scopus)
• 2019

  Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

  Lee, R. S., Zhang, L., Berger, A., Lawrence, M. G., Song, J., Niranjan, B., Davies, R. G., Lister, N. L., Sandhu, S. K., Rubin, M. A., Risbridger, G. P., Taylor, R. A., Rickman, D. S., Horvath, L. G. & Daly, R. J., 1 Apr 2019, In: Neoplasia. 21, 4, p. 389-400 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  16 Citations (Scopus)

• Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment

  Nguyen, E. V., Pereira, B. A., Lawrence, M. G., Ma, X., Rebello, R. J., Chan, H., Niranjan, B., Wu, Y., Ellem, S., Guan, X., Wu, J., Skhinas, J. N., Cox, T. R., Risbridger, G. P., Taylor, R. A., Lister, N. L. & Daly, R. J., 1 Jul 2019, In: Molecular & Cellular Proteomics. 18, 7, p. 1410-1427 18 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  58 Citations (Scopus)

• Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

  Watt, M. J., Clark, A. K., Selth, L. A., Haynes, V. R., Lister, N., Rebello, R., Porter, L. H., Niranjan, B., Whitby, S. T., Lo, J., Huang, C., Schittenhelm, R. B., Anderson, K. E., Furic, L., Wijayaratne, P. R., Matzaris, M., Montgomery, M. K., Papargiris, M., Norden, S., Febbraio, M., & 4 othersRisbridger, G. P., Frydenberg, M., Nomura, D. K. & Taylor, R. A., 6 Feb 2019, In: Science Translational Medicine. 11, 478, 12 p., eaau5758.

  Research output: Contribution to journal › Article › Research › peer-review
  180 Citations (Scopus)

• The influence of BRCA2 mutation on localized prostate cancer

  Taylor, R. A., Fraser, M., Rebello, R. J., Boutros, P. C., Murphy, D. G., Bristow, R. G. & Risbridger, G. P., 1 May 2019, In: Nature Reviews Urology. 16, 5, p. 281-290 10 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  52 Citations (Scopus)

• Tissue engineered human prostate microtissues reveal key role of mast cell-derived tryptase in potentiating cancer-associated fibroblast (CAF)-induced morphometric transition in vitro

  Pereira, B. A., Lister, N. L., Hashimoto, K., Teng, L., Flandes-Iparraguirre, M., Eder, A., Sanchez-Herrero, A., Niranjan, B., Melbourne Urological Research Alliance (MURAL), Frydenberg, M., Papargiris, M. M., Lawrence, M. G., Taylor, R. A., Hutmacher, D. W., Ellem, S. J., Risbridger, G. P. & De-Juan-Pardo, E. M., 1 Mar 2019, In: Biomaterials. 197, p. 72-85 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  34 Citations (Scopus)

• Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

  Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., Chen, S., Lawrence, M. G., Szkop, K. J., Samreen, B., Balanathan, P., Rapino, F., Close, P., Bukczynska, P., Scharmann, K., Takizawa, I., Risbridger, G. P., Selth, L. A., Leidel, S. A., Lin, Q., & 3 othersTopisirovic, I., Larsson, O. & Furic, L., 2 Dec 2019, In: The EMBO Journal. 38, 23, 19 p., e101323.

  Research output: Contribution to journal › Article › Research › peer-review
  24 Citations (Scopus)
• 2018

  Enduring epigenetic landmarks define the cancer microenvironment

  Pidsley, R., Lawrence, M. G., Zotenko, E., Niranjan, B., Statham, A., Song, J., Chabanon, R. M., Qu, W., Wang, H., Richards, M., Nair, S. S., Armstrong, N., Nim, H. T., Papargiris, M., Balanathan, P., French, H., Peters, T., Norden, S., Ryan, A., Pedersen, J., & 9 othersKench, J. G., Daly, R. J., Horvath, L., Stricker, P., Frydenberg, M., Taylor, R. A., Stirzaker, C., Risbridger, G. P. & Clark, S. J., 1 May 2018, In: Genome Research. 28, 5, p. 625-638 14 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  67 Citations (Scopus)

• Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

  Porter, L. H., Hashimoto, K., Lawrence, M. G., Pezaro, C., Clouston, D., Wang, H., Papargiris, M., Thorne, H., Li, J., kConFab Investigators, Ryan, A., Norden, S., Moon, D., Bolton, D. M., Sengupta, S., Frydenberg, M., Murphy, D. G., Risbridger, G. P. & Taylor, R. A., 1 Jun 2018, In: BJU International. 121, 6, p. 971-978 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  37 Citations (Scopus)

• Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

  Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S., & 32 othersHuglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., 1 Nov 2018, In: European Urology. 74, 5, p. 562-572 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  66 Citations (Scopus)
• 2017

  Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

  Lee, S. N., Chakrabarty, B., Wittmer, B., Papargiris, M., Ryan, A., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Risbridger, G. P., Ellem, S. J. & Exintaris, B., 1 Dec 2017, In: Scientific Reports. 7, 1, 9 p., 10150.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

• Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

  Kryza, T., Silva, L. M., Bock, N., Fuhrman-Luck, R. A., Stephens, C. R., Gao, J., Samaratunga, H., Australian Prostate Cancer BioResource, Lawrence, M. G., Hooper, J. D., Dong, Y., Risbridger, G. P. & Clements, J. A., 1 Oct 2017, In: Molecular Oncology. 11, 10, p. 1307-1329 23 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)

• Mammary stem cells and parity-induced breast cancer protection- new insights

  Dall, G., Risbridger, G. & Britt, K., Jun 2017, In: Journal of Steroid Biochemistry and Molecular Biology. 170, p. 54-60 7 p.

  Research output: Contribution to journal › Review Article › Other › peer-review
  23 Citations (Scopus)

• Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories

  Porter, L. H., Lawrence, M. G., Ilic, D., Clouston, D., Bolton, D. M., Frydenberg, M., Murphy, D. G., Pezaro, C., Risbridger, G. P. & Taylor, R. A., Oct 2017, In: European Urology. 72, 4, p. 492-495 4 p.

  Research output: Contribution to journal › Article › Research › peer-review
  71 Citations (Scopus)

• Towards best practice in establishing patient-derived xenografts

  Risbridger, G. P. & Lawrence, M. G., 30 Jun 2017, Patient-Derived Xenograft Models of Human Cancer. Wang, Y., Lin, D. & Gout, P. W. (eds.). 1st ed. Springer, p. 11-28 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
• 2015

  Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer

  Lawrence, M. G., Pook, D. W., Wang, H., Porter, L. H., Frydenberg, M., Kourambas, J., Appu, S., Poole, C., Beardsley, E. K., Ryan, A. J., Norden, S., Papargiris, M., Risbridger, G. P. & Taylor, R. A., 2015, In: The Prostate. 75, 13, p. 1475 - 1483 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  30 Citations (Scopus)

• Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity

  Takizawa, I., Lawrence, M. G., Balanathan, P., Rebello, R., Pearson, H. B., Garg, E., Pedersen, J. S., Pouliot, N., Nadon, R., Watt, M. J., Taylor, R. A., Humbert, P. O., Topisirovic, I., Larsson, O., Risbridger, G. P. & Furic, L., 2015, In: Oncotarget. 6, 2, p. 604 - 616 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  37 Citations (Scopus)
• 2014

  A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

  Ellem, S. J., Taylor, R. A., Furic, L., Larsson, O., Frydenberg, M., Pook, D. W., Pedersen, J. S., Cawsey, B., Trotta, A., Need, E. F., Buchanan, G. & Risbridger, G. P., 2014, In: Journal of Pathology. 234, 1, p. 86 - 98 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  40 Citations (Scopus)

• Cross-species stromal signaling programs human embryonic stem cell differentiation

  Taylor, R. A. & Risbridger, G. P., 2014, In: Differentiation. 87, 1-2, p. 76 - 82 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  1 Citation (Scopus)