Novel homogeneous catalysis strategies will be used to generate well defined peptide polymers. The resulting polymer targets will be biomimetics of unique-functioning natural proteins. Stable analogues of antifreeze proteins, which are non-toxic and inhibit ice nucleation at extremely low concentrations in sub-Arctic animal and plant species, are needed for medical applications (organ/cell preservation) and food preservation. Resilin, a bioelastomer found in insects, is a near perfect rubber with extraordinary fatigue life. Structural mimetics will find medical (implants -heart valves, spinal discs) and industrial (accelerometers/actuators) uses. Polymerisation of immunogenic segments of infectious diseases will lead to synthetic vaccines.
|Effective start/end date||2/01/08 → 31/12/12|
- Australian Research Council (ARC): A$235,944.00
- Australian Research Council (ARC): A$174,056.00
- Monash University