Project Details
Project Description
The project aims to realise new selective and efficient alkyne cyclization strategies to the carbocyclic and
heterocyclic family of compounds, which is immensely important because of their various synthetic, biological and
materials applications. This would be demonstrated by identifying new green and sustainable synthetic methods
based on minimising and/or eliminating the consumption of various material and energy resources and chemical
waste production. The newly developed catalytic methodologies would serve as new synthetic tools that will highly
impact current thinking in organic chemistry and significantly contribute new and efficient conceptual chemical
processes to all sectors of the academic, chemical and pharmaceutical communities.
heterocyclic family of compounds, which is immensely important because of their various synthetic, biological and
materials applications. This would be demonstrated by identifying new green and sustainable synthetic methods
based on minimising and/or eliminating the consumption of various material and energy resources and chemical
waste production. The newly developed catalytic methodologies would serve as new synthetic tools that will highly
impact current thinking in organic chemistry and significantly contribute new and efficient conceptual chemical
processes to all sectors of the academic, chemical and pharmaceutical communities.
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/16 → 31/12/19 |
Funding
- ARC - Australian Research Council: A$499,671.00
- Monash University
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A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer
Li, G., Henry, S. A., Liu, H., Kang, T.-S., Nao, S.-C., Zhao, Y., Wu, C., Jin, J., Zhang, J., Leung, C.-H. D., Chan, P. W. H. & Ma, D.-L. E., 10 Jan 2020, In: Chemical Science. 11, 7, p. 1750-1760 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access36 Link opens in a new tab Citations (Scopus) -
Copper catalyzed: N-formylation of α-silyl-substituted tertiary N-alkylamines by air
Zhao, Y., Bruce, L. D., Jin, J., Xia, B. & Chan, P. W. H., 21 Aug 2020, In: Green Chemistry. 22, 16, p. 5296-5302 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile10 Link opens in a new tab Citations (Scopus) -
Gold and Brønsted Acid Catalyzed Spirocyclization of 2- and 3-Indolyl-Tethered 1,4-Enyne Acetates to Spiro[4, n]alkyl[ b]indoles
Chen, X., Baratay, C. A., Mark, M. E., Xu, X. & Hong Chan, P. W., 3 Apr 2020, In: Organic Letters. 22, 7, p. 2849-2853 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile19 Link opens in a new tab Citations (Scopus)