Mucus Control – Applying concepts from bacteriophage-mucus interactions.

Project: Research

Project Description

This project aims to examine how mucus-adherent bacteriophage interact with bacteria in mucus as a novel mechanism to manipulate microbiomes. Bacterial infections at mucosal surfaces in animals represent a serious global health threat. Traditionally antibiotics have been used to curb mucosal infections. But with the rise of antibiotic resistance, new therapies are urgently needed. Bacteriophage – viruses that infect bacteria – have evolved many unique and auspicious ways to kill bacteria and they have recently been hypothesised to provide a novel layer of antimicrobial immunity in animal mucus. The anticipated goal is to resolve how bacteriophage control bacteria within mucus, and apply concepts toward bioengineering of mucosal microbiomes.
StatusFinished
Effective start/end date1/01/1731/12/19