Morphological development of the kidney - a paradigm for organogenesis.

  • Smyth, Ian (Primary Chief Investigator (PCI))
  • Hamilton, Nicholas (Chief Investigator (CI))
  • Henkelman, Mark (Chief Investigator (CI))

Project: Research

Project Description

This project Aims to investigate a remarkable mathematical pattern that we have discovered in the program of
branching morphogenesis which dictates kidney development. By combining cutting edge genetic approaches,
morphological analysis and mathematical modelling this project will explore how this pattern is established, how it
dictates kidney development and whether it constitutes an ancient mechanism central to organ formation. In doing
so the project will shed light on a fundamental developmental processes and it is anticipated that the findings will
considerably impact our understanding of developmental disease and variation, and will be important for
understanding the development of other organ systems.
StatusFinished
Effective start/end date1/01/161/06/19

Funding

  • Australian Research Council (ARC): AUD488,100.00
  • Monash University
  • University of Queensland
  • University of Toronto
  • University of Queensland