Molecular mechanism for the regulation of Polycomb repressive complex 2

Project: Research

Status	Not started

Allosteric regulation of histone lysine methyltransferases: From context-specific regulation to selective drugs
Davidovich, C. & Zhang, Q., Apr 2021, In: Biochemical Society Transactions. 49, 2, p. 591-607 17 p.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access

6 Citations (Scopus)
PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis
Zhang, Q., Agius, S. C., Flanigan, S. F., Uckelmann, M., Levina, V., Owen, B. M. & Davidovich, C., Dec 2021, In: Nature Communications. 12, 1, 18 p., 4592.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

28 Citations (Scopus)
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2
Zhang, Q., McKenzie, N. J., Warneford-Thomson, R., Gail, E. H., Flanigan, S. F., Owen, B. M., Lauman, R., Levina, V., Garcia, B. A., Schittenhelm, R. B., Bonasio, R. & Davidovich, C., 4 Mar 2019, In: Nature Structural & Molecular Biology. 26, 3, p. 237-247 11 p.
Research output: Contribution to journal › Article › Research › peer-review

85 Citations (Scopus)

Project Details