Molecular Machines: regulation of the catalysis and rotation of the enzyme ATP Synthase

Project: Research

Project Details

Project Description

This project aims to elucidate the regulation of the molecular machine ATP synthase. ATP synthase is an enzyme that performs a critical role in all cells - the synthesis of ATP, the universal biological energy currency. It is known that the enzyme operates via rotation of a central stalk, which is driven by a hydrogen ion gradient across a membrane. Constructs of this molecule have been envisaged in the design of future biological nano-motors. Our work will provide an understanding of the regulation of this enzyme with potential application in the control of nano-motors.
StatusFinished
Effective start/end date1/01/0331/12/06

Funding

  • Australian Research Council (ARC): AUD110,000.00