Molecular control of efficacy at glucagon family of receptors

Project: Research

Status	Active
Effective start/end date	1/01/20 → 31/12/24

National Health and Medical Research Council (NHMRC) (Australia): AUD1,348,640.00

Evolving cryo-EM structural approaches for GPCR drug discovery
Zhang, X., Johnson, R. M., Drulyte, I., Yu, L., Kotecha, A., Danev, R., Wootten, D., Sexton, P. M. & Belousoff, M. J., 2 Sep 2021, In: Structure. 29, 9, p. 963-974.e6 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
Yuliantie, E., van der Velden, W. J. C., Labroska, V., Dai, A., Zhao, F., Darbalaei, S., Deganutti, G., Xu, T., Zhou, Q., Yang, D., Rosenkilde, M. M., Sexton, P. M., Wang, M. W. & Wootten, D., Oct 2021, In: Biochemical Pharmacology. 192, 16 p., 114715.
Research output: Contribution to journal › Article › Research › peer-review
Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes
Zhang, X., Belousoff, M. J., Liang, Y. L., Danev, R., Sexton, P. M. & Wootten, D., 13 Jul 2021, In: Cell Reports. 36, 2, 15 p., 109374.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)

Project Details