Molecular characterisation of pore-forming proteins as pest control agents

Project: Research

Project Details

Project Description

This project aims to utilise protein engineering, structural biology, and biochemistry to characterise the function of
key members of the aerolysin/epsilon toxin/Toxin_10 pore-forming protein superfamily. Pore formation is a ubiquitous mechanism deployed by all kingdoms as defences against invading organisms. The expected outcomes of this project include the development of novel techniques aimed, broadly, at studying pore-forming proteins during the assembly pathway. This project should be of benefit to the wider research community by improving our understanding of pore-forming proteins as potential pest control agents.
StatusNot started
Effective start/end date28/06/2427/06/27

Funding

  • Australian Research Council (ARC): A$327,237.00
  • Australian Research Council (ARC): A$107,763.00
  • Monash University – Internal Department Contribution: A$285,251.00