Molecular basis for control of DNA transcription of housekeeping genes

  • Elmlund, Hans (Primary Chief Investigator (PCI))
  • Robinson, Carol (Partner Investigator (PI))

Project: Research

Project Details

Project Description

The development of a multicellular organism requires expression of many thousands of different messenger RNAs, at exactly the right time, in the right set of cells and in the right amount. Thus, the need for stringent regulation gene expression arises. This Project aims at understanding how 90% of all eukaryotic genes are regulated. The data will show how a massive protein complex of ~50 individual gene products'the general transcription machinery'identifies the start site of a gene, recruits RNA polymerase II and prepares it for transcription of the genetic code.
StatusFinished
Effective start/end date1/01/1731/12/19

Funding

  • Australian Research Council (ARC): AUD399,500.00
  • Monash University: AUD9,948.00
  • University of Oxford