Modulating Inflammatory and Fibrogenic Pathways in Kidney Disease using a novel antagonist of Protease-Activated-Receptor-2

Nikolic-Paterson, David (Primary Chief Investigator (PCI))
Gobe, Glenda (Chief Investigator (CI))
Lohman, Rink-Jan (Chief Investigator (CI))
Suen, Jacky (Chief Investigator (CI))
Vesey, David (Chief Investigator (CI))

Medicine Monash Health

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/17

Funding

NHMRC - National Health and Medical Research Council (Australia): A$199,718.00

PAR2 activation on human tubular epithelial cells engages converging signaling pathways to induce an inflammatory and fibrotic milieu
Vesey, D. A., Iyer, A., Owen, E., Kamato, D., Johnson, D. W., Gobe, G. C., Fairlie, D. P. & Nikolic-Paterson, D. J., 2024, In: Frontiers in Pharmacology. 15, 15 p., 1382094.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Link opens in a new tab Citations (Scopus)
PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting
Iyer, A., Humphries, T. L. R., Owens, E. P., Zhao, K. N., Masci, P. P., Johnson, D. W., Nikolic-Paterson, D., Gobe, G. C., Fairlie, D. P. & Vesey, D. A., 10 Mar 2021, In: Frontiers in Physiology. 12, 14 p., 615428.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

11 Link opens in a new tab Citations (Scopus)
Par2-induced tissue factor synthesis by primary cultures of human kidney tubular epithelial cells is modified by glucose availability
Humphries, T. L. R., Shen, K., Iyer, A., Johnson, D. W., Gobe, G. C., Nikolic-Paterson, D., Fairlie, D. P. & Vesey, D. A., 2 Jul 2021, In: International Journal of Molecular Sciences. 22, 14, 12 p., 7532.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

7 Link opens in a new tab Citations (Scopus)