Mechanistic understanding of biased agonism and dimerisation for co-targeting incretin receptors for metabolic diseases

Wootten, Denise (Primary Chief Investigator (PCI))

Drug Discovery Biology

Project: Research

Status	Active
Effective start/end date	1/01/24 → 31/12/28

1 Article

Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein
Cao, J., Belousoff, M. J., Danev, R., Christopoulos, A., Wootten, D. & Sexton, P. M., 7 May 2024, In: Biochemistry. 63, 9, p. 1089-1096 8 p.
Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

MASSIVE
David Powell (Manager) & Gin Tan (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
Ramaciotti Centre for Cryo-Electron Microscopy
Georg Ramm (Manager), Simon Andrew Crawford (Operator), Hariprasad Venugopal (Operator), Joan Marea Clark (Operator) & Gediminas Gervinskas (Operator)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility