Mechanisms underlying the contribution of uremic toxins to cardiorenal syndrome

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/17

Apoptosis signal-regulating kinase 1 inhibition reverses deleterious indoxyl sulfate-mediated endothelial effects
Savira, F., Kompa, A. R., Magaye, R., Xiong, X., Huang, L., Jucker, B. M., Willette, R. N., Kelly, D. J. & Wang, B. H., 1 May 2021, In: Life Sciences. 272, 9 p., 119267.
Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)
Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells
Magaye, R. R., Savira, F., Hua, Y., Xiong, X., Huang, L., Reid, C., Flynn, B. L., Kaye, D., Liew, D. & Wang, B. H., May 2021, In: International Journal of Biochemistry & Cell Biology. 134, 16 p., 105952.
Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)
Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts
Magaye, R. R., Savira, F., Xiong, X., Huynh, K., Meikle, P. J., Reid, C., Flynn, B. L., Kaye, D., Liew, D. & Wang, B. H., Aug 2021, In: IJC Heart & Vasculature. 35, 11 p., 100837.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

5 Citations (Scopus)

Project Details