Masterminding Reproduction: Kisspeptin and RFamide-Related Peptide

The search for critical regulators of reproduction has remained the holy grail for reproductive endocrinologists for over 30 years. The answer may finally be at hand and we are at the epicentre of this research. This proposal aims to further explore the functional significance of the brain peptide hormones kisspeptin and RF-related peptide in the central control of reproduction. The project will do this by delineating structural and functional connections within the brain and detail the role each plays in controlling hormones from the brain that govern puberty and reproduction. Results will have far reaching implications for the treatment of infertility and reproductive cancers.