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LEADER-PAD: A Trial of Low Dose Colchicine in Peripheral Arterial Disease

  • Jansen, Shirley (Primary Chief Investigator (PCI))
  • Thompson, Peter Lindsay (Chief Investigator (CI))
  • Reid, Christopher (Chief Investigator (CI))
  • Golledge, Jonathan (Chief Investigator (CI))
  • Eikelboom, John William (Chief Investigator (CI))
  • Mosterd, Arend (Chief Investigator (CI))
  • Norman, Richard (Chief Investigator (CI))
  • Chih, Huijun (Chief Investigator (CI))
  • Chan, Noel (Chief Investigator (CI))
  • Aitken, Sarah Joy (Chief Investigator (CI))
  • Frahm-Jensen, Gert (Chief Investigator (CI))
  • Delaney, Christopher (Chief Investigator (CI))
  • Bond, Richard (Chief Investigator (CI))
  • Altaf, Nishath (Chief Investigator (CI))
  • Thurston, Benjamin (Chief Investigator (CI))
  • Dear, Anthony (Associate Investigator (AI))
  • Khashram, Manar (Associate Investigator (AI))
  • Lyons, Oliver (Associate Investigator (AI))
  • Lo, Zhiwen Joseph (Associate Investigator (AI))
  • Qasabian, Raffi (Associate Investigator (AI))

Project: Research

Project Details

Project Description

This application proposes an Australian colchicine trial as part of the international Phase III LEADER PAD trial. Overall, the study will provide evidence of the effectiveness of colchicine in improving cardiovascular health and reducing the risk of complications in patients with high-risk peripheral artery disease.
AcronymLEADER-PAD
StatusActive
Effective start/end date23/02/24 → 30/06/28

Keywords

  • cardiovascular health
  • cardiovascular disease
  • chronic inflammation
  • treatment efficacy
  • anti-inflammatory