The goal of this experiment is to understand how stem cells interact with their local environment and maintain the status quo in organs and tissues throughout life. How do stem cells generate daughter cells of their own, and not other tissue types, so mammary stem cells make mammary glands and not prostate glands, during tissue turnover and maintenance? The predicted novel outcome is that the environment can orchestrate and direct stem cell fate and we will reveal key pathways that instruct these decisions. These findings will be significant to investigators working in diverse developmental systems and for stem cell biologists working on tissue regeneration.
|Effective start/end date||1/01/09 → 31/12/11|
- Australian Research Council (ARC): AUD190,000.00
- Australian Research Council (ARC): AUD117,000.00
- Australian Research Council (ARC)