Isoform selective PI3 kinase inhibitors for cancer, thrombosis and inflammatory disease

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/16

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ
Miller, M. S., Mountford, S. J., Pinson, J-A., Zheng, Z., Künzli, M., Patel, V., Hogg, S. J., Shortt, J., Jennings, I. G. & Thompson, P. E., 1 Oct 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 19, p. 4790-4794 5 p.
Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)
Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)
Zheng, Z., Pinson, J. A., Mountford, S. J., Orive, S., Schoenwaelder, S. M., Shackleford, D., Powell, A., Nelson, E. M., Hamilton, J. R., Jackson, S., Jennings, I. G. & Thompson, P. E., 21 Oct 2016, In: European Journal of Medicinal Chemistry. 122, p. 339-351 13 p.
Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)

Project Details