Investigation of small molecule interactions with the human leukocyte antigen and their role in non-infectious disease

Illing, Patricia (Primary Chief Investigator (PCI))

Biochemistry & Molecular Biology

Project: Research

Status	Finished
Effective start/end date	1/01/14 → 31/12/17

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$304,596.00

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11 Article
2 Review Article

Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition
Mifsud, N. A., Illing, P. T., Lai, J. W., Fettke, H., Hensen, L., Huang, Z., Rossjohn, J., Vivian, J. P., Kwan, P. & Purcell, A. W., 12 Apr 2021, In: Frontiers in Immunology. 12, 20 p., 653710.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C., Cheng, A. C. & 16 others, Richards, M., Westall, G. P., Wakim, L. M., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Jackson, D. C., Flanagan, K. L., Rossjohn, J., Gras, S., Davies, J., Miller, A., Tong, S. Y. C., Purcell, A. W. & Kedzierska, K., 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

5 Citations (Scopus)
Kinetics of Abacavir-Induced Remodelling of the Major Histocompatibility Complex Class I Peptide Repertoire
Illing, P. T., van Hateren, A., Darley, R., Croft, N. P., Mifsud, N. A., King, S., Kostenko, L., Bharadwaj, M., McCluskey, J., Elliott, T. & Purcell, A. W., 19 May 2021, In: Frontiers in Immunology. 12, 19 p., 672737.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

4 Citations (Scopus)

Australian Synchrotron
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

Investigation of small molecule interactions with the human leukocyte antigen and their role in non-infectious disease

Project Details

Funding

Research output

Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

Kinetics of Abacavir-Induced Remodelling of the Major Histocompatibility Complex Class I Peptide Repertoire

Equipment

Australian Synchrotron

CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph