Investigating the contribution of distinct mitochondrial cell death pathways to platelet survival and function

Project: Research

Status	Finished
Effective start/end date	1/01/12 → 31/05/15

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion
Pleines, I., Lebois, M., Gangatirkar, P., Au, A. E., Lane, R. M., Henley, K. J., Kauppi, M., Corbin, J., Cannon, P., Bernardini, J., Alwis, I., Jarman, K. E., Ellis, S., Metcalf, D., Jackson, S. P., Schoenwaelder, S. M., Kile, B. T. & Josefsson, E. C., 12 Jul 2018, In: Blood. 132, 2, p. 197-209 13 p.
Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)
Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia
Yuan, Y., Alwis, I., Wu, M. C. L., Kaplan, Z., Ashworth, K., Bark, D., Pham, A., McFadyen, J., Schoenwaelder, S. M., Josefsson, E. C., Kile, B. T. & Jackson, S. P., 27 Sep 2017, In: Science Translational Medicine. 9, 409, 14 p., eaam5861.
Research output: Contribution to journal › Article › Research › peer-review

35 Citations (Scopus)
Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells
Samson, A. L., Ho, B., Au, A. E., Schoenwaelder, S. M., Smyth, M. J., Bottomley, S. P., Kleifeld, O. & Medcalf, R. L., 2016, In: Biology Open. 6, 11, 12 p., 160098.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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5 Citations (Scopus)

Project Details