Insulin-like frowth factors are important for normal growth and development. Their actions are requlated by a family of IGF binding proteins. In order to understand the mechanism of this regulation, the aim of this project is to determine the 3-dimensional structure of 2 IGFBPs in complex with IGFs. This will lead to a comprehensive understanding of this interaction that promises to provide important basic knowledge as well as having major implications for biotechnology, agriculture and health.
|Effective start/end date||1/01/04 → 31/12/07|
- Australian Research Council (ARC): AUD156,701.00