Inhibitors of dengue virus nonstructural protein 5 nuclear trafficking as probes of dengue biology

Project: Research

Status	Finished
Effective start/end date	1/01/14 → 30/09/17

Dynamic nucleolar targeting of dengue virus polymerase NS5 in response to extracellular pH
Fraser, J. E., Rawlinson, S. M., Heaton, S. M. & Jans, D. A., Jun 2016, In: Journal of Virology. 90, 12, p. 5797-5807 11 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

18 Citations (Scopus)
Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R–like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells
Fraser, J. E., Wang, C., Chan, K. W. K., Vasudevan, S. G. & Jans, D. A., Jun 2016, In: Antiviral Research. 130, 6 p.
Research output: Contribution to journal › Article › Research › peer-review

26 Citations (Scopus)
A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection
Fraser, J. E., Watanabe, S., Wang, C., Chan, W. K. K., Maher, B., Lopez-Denman, A., Hick, C. A., Wagstaff, K. M., Mackenzie, J. M., Sexton, P. M., Vasudevan, S. G. & Jans, D. A., 2014, In: The Journal of Infectious Diseases. 210, 11, p. 1780 - 1791 12 p.
Research output: Contribution to journal › Article › Research › peer-review

92 Citations (Scopus)

Project Details