Immune balance-regulating interleukins as targets for immunotherapy

Yu, Di (Primary Chief Investigator (PCI))

Project: Research

Status	Relinquished
Effective start/end date	1/01/15 → 30/12/16

Funding

NHMRC - National Health and Medical Research Council (Australia): A$455,452.00

6 Article
1 Short Survey
1 Review Article

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation
Chen, Z., Cui, Y., Yao, Y., Liu, B., Yunis, J., Gao, X., Wang, N., Cañete, P. F., Tuong, Z. K., Sun, H., Wang, H., Yang, S., Wang, R., Leong, Y. A., Davis, D. S., Qin, J., Liang, K., Deng, J., Wang, C. K. & Huang, Y. H. & 10 others, Roco, J. A., Nettelfield, S., Zhu, H., Xu, H., Yu, Z., Craik, D., Liu, Z., Qi, H., Parish, C. & Yu, D., Feb 2023, In: Science Immunology. 8, 80, 17 p., eadd1728.
Research output: Contribution to journal › Article › Research › peer-review

40 Citations (Scopus)
Selenium–GPX4 axis protects follicular helper T cells from ferroptosis
Yao, Y., Chen, Z., Zhang, H., Chen, C., Zeng, M., Yunis, J., Wei, Y., Wan, Y., Wang, N., Zhou, M., Qiu, C., Zeng, Q., Ong, H. S., Wang, H., Makota, F. V., Yang, Y., Yang, Z., Wang, N., Deng, J. & Shen, C. & 19 others, Xia, Y., Yuan, L., Lian, Z., Deng, Y., Guo, C., Huang, A., Zhou, P., Shi, H., Zhang, W., Yi, H., Li, D., Xia, M., Fu, J., Wu, N., de Haan, J. B., Shen, N., Zhang, W., Liu, Z. & Yu, D., Sept 2021, In: Nature Immunology. 22, 9, p. 1127-1139 13 p.
Research output: Contribution to journal › Article › Research › peer-review

299 Citations (Scopus)
The metabolic hormone leptin promotes the function of T_FH cells and supports vaccine responses
Deng, J., Chen, Q., Chen, Z., Liang, K., Gao, X., Wang, X., Makota, F. V., Ong, H. S., Wan, Y., Luo, K., Gong, D., Yu, X., Camuglia, S., Zeng, Q., Zhou, T., Xue, F., He, J., Wei, Y., Xiao, F. & Ma, J. & 17 others, Hill, D. L., Pierson, W., Nguyen, T. H. O., Zhou, H., Wang, Y., Shen, W., Sun, L., Li, Z., Xia, Q., Qian, K., Ye, L., Rockman, S., Linterman, M. A., Kedzierska, K., Shen, N., Lu, L. & Yu, D., Dec 2021, In: Nature Communications. 12, 1, 15 p., 3073.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

37 Citations (Scopus)

Australian Synchrotron
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

Immune balance-regulating interleukins as targets for immunotherapy

Project Details

Funding

Research output

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

Equipment

Australian Synchrotron

The metabolic hormone leptin promotes the function of T_FH cells and supports vaccine responses