Immobilised Lipid Chromatography for Membrane Protein Isolation and Analysis

Project: Research

Project Details

Project Description

Current techniques for membrane protein are inadequate for the emerging proteomic challenge, in which approximately 40% of proteins are predicted to be membrane associated. The aim of this proposal is to develop a new approach to purify membrane proteins using our recently-developed immobilised membrane chromatography materials. The present proposal will provide a new high-resolution separation technique that allows isolation and on-line mass analysis of complex mixtures of membrane proteins for subsequent proteomic analysis, high-throughput screening or structural studies and could form the basis for further development of new commercial tools for membrane protein analysis.
StatusFinished
Effective start/end date1/01/043/12/06

Funding

  • Australian Research Council (ARC): AUD240,000.00