Identification of the molecular mechanisms by which mutations in FHL1 lead to protein misfolding and skeletal muscle disease

Mitchell, Christina (Primary Chief Investigator (PCI))
Mcgrath, Meagan (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/11 → 31/12/13

Funding

NHMRC - National Health and Medical Research Council (Australia): A$588,390.00

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1)
Feeney, S. J., Mcgrath, M. J., Sriratana, A., Gehrig, S. M., Lynch, G. S., D'Arcy, C. E., Price, J. T., McLean, C. A., Tupler, R. & Mitchell, C. A., 19 Feb 2015, In: PLoS ONE. 10, 2, 29 p., e0117665.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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8 Link opens in a new tab Citations (Scopus)
199th ENMC international workshop: FHL1 related myopathies, June 7-9, 2013, Naarden, The Netherlands
Bertrand, A. T., Bonnemann, C. G., Bonne, G., Mitchell, C. A. & Mcgrath, M. J., 2014, In: Neuromuscular Disorders. 24, 5, p. 453 - 462 10 p.
Research output: Contribution to journal › Article › Other

Open Access
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14 Link opens in a new tab Citations (Scopus)
FHL1 mutants that cause clinically distinct human myopathies form protein aggregates and impair myoblast differentiation
Wilding, B. R., Mcgrath, M. J., Bonne, G. & Mitchell, C. A., 2014, In: Journal of Cell Science. 127, 10, p. 2269 - 2281 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

28 Link opens in a new tab Citations (Scopus)