Identification and targeting of a potent NK cell “checkpoint” in tumour immunity

Project: Research

Status	Finished
Effective start/end date	1/02/19 → 31/12/20

The Ratio of Exhausted to Resident Infiltrating Lymphocytes Is Prognostic for Colorectal Cancer Patient Outcome
Foroutan, M., Molania, R., Pfefferle, A., Behrenbruch, C., Scheer, S., Kallies, A., Speed, T. P., Cursons, J. & Huntington, N. D., 1 Oct 2021, In: Cancer Immunology Research. 9, 10, p. 1125-1140 16 p.
Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)
Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection
Gabriel, S. S., Tsui, C., Chisanga, D., Weber, F., Llano-León, M., Gubser, P. M., Bartholin, L., Souza-Fonseca-Guimaraes, F., Huntington, N. D., Shi, W., Utzschneider, D. T. & Kallies, A., 10 Aug 2021, In: Immunity. 54, 8, p. 1698-1714.e5 23 p.
Research output: Contribution to journal › Article › Research › peer-review

107 Citations (Scopus)
Drug target validation in primary human natural killer cells using CRISPR RNP
Rautela, J., Surgenor, E. & Huntington, N. D., Oct 2020, In: Journal of Leukocyte Biology. 108, 4, p. 1397-1408 12 p.
Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Project Details