Hyphenated Separations/Mass Spectrometry Technology for Protein and Natural Product Characterisation

  • Hearn, Milton (Primary Chief Investigator (PCI))
  • Haddad, Paul (Chief Investigator (CI))
  • Marriott, Philip (Chief Investigator (CI))

Project: Research

Project Description

This proposal consolidates the 3 institutions' collaboration on the ACROSS (Australian Centre for Research on Separation Science) initiative, providing fundamental technology for chemical structural analysis of complex smaples involving high resolution protein and natural product characterisation. Requested equipment supports complete characterisation of important novel target molecules. GCxGC-TOFMS technology will validate our newly patented multidimensional separation techniques. Q-TOF-TOFMS technology, novel patented protein prefractionation approaches, and sample handling with high resolution characterisation/identification of new target proteins allows advanced proteomics developments/ Proteomics depends critically upon sophisticated MS techniques. These technologies will: enhance the capabilities and expertise in these sciencces in the SE Australian area; ensure the ACROSS initiative achieves internationally competitive research apabilities; provide commercial endpoints in fields associated with analysis of proteins, essential oils and other natural (bio)substances.
StatusFinished
Effective start/end date1/01/0231/12/02

Funding

  • Australian Research Council (ARC): AUD707,000.00
  • Monash University: AUD55,000.00
  • Monash University: AUD110,000.00
  • RMIT University
  • University of Tasmania
  • RMIT University
  • Australian Research Council (ARC)