Human pancreatic ductal cell-driven beta-cell regeneration

El-Osta, Sam (Primary Chief Investigator (PCI))
Cooper, Mark (Chief Investigator (CI))
Al-Hasani, Keith (Chief Investigator (CI))
Loudovaris, Thomas (Associate Investigator (AI))
Khurana, Ishant (Associate Investigator (AI))

Diabetes

Project: Research

2 Article

2 results

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2024

The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity
Esser, N., Hogan, M. F., Templin, A. T., Akter, R., Fountaine, B. S., Castillo, J. J., El-Osta, A., Manathunga, L., Zhyvoloup, A., Raleigh, D. P., Zraika, S., Hull, R. L. & Kahn, S. E., Sept 2024, In: Diabetologia. 67, 9, p. 1897-1911 15 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
2022

Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor
Al-Hasani, K., Khurana, I., Mariana, L., Loudovaris, T., Maxwell, S., Harikrishnan, K. N., Okabe, J., Cooper, M. E. & El-Osta, A., 22 Jul 2022, In: Signal Transduction and Targeted Therapy. 7, 1, 9 p., 248.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

13 Citations (Scopus)