Holistic Approach in Primary care for PreventIng Memory Impairment and Dementia

  • George, Johnson (Primary Chief Investigator (PCI))
  • Magin, Parker (Chief Investigator (CI))
  • Baker, Amanda L. (Chief Investigator (CI))
  • Bonevski, Billie (Chief Investigator (CI))
  • Ward, Stephanie Alison (Chief Investigator (CI))
  • Mahal, Ajay S. (Chief Investigator (CI))
  • Versace, Vincent Lawrence (Chief Investigator (CI))
  • Bell, Simon (Chief Investigator (CI))
  • McNamara, Kevin (Chief Investigator (CI))
  • O'Reilly, Sharleen L. (Chief Investigator (CI))

Project: Research

Project Details

Project Description

The aim is to implement a general practice-based holistic dementia risk assessment and health promotion program suitable for all Australians and evaluate its cost effectiveness. A cluster randomised controlled trial (cRCT) will be carried out in 40 general practice clinics across New South Wales and Victoria. Community dwelling adults aged 45 years – 65 years with two or more risk factors for cognitive impairment will be recruited from each clinic. Change in risk factors for dementia measured using the Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI) will be the primary outcome. ANU-ADRI is an evidence-based, validated tool aimed at assessing individual exposure to risk factors known to be associated with an increased risk of developing Alzheimer's disease in late-life. The intervention will be implemented, evaluated and reported according to the Medical Research Council Framework for the Development and Evaluation of RCTs for Complex Interventions to Improve Health.
Short titleImplementing Dementia Risk Reduction and Prevention
Effective start/end date1/08/1931/07/25


  • National Health and Medical Research Council (NHMRC) (Australia): A$1,999,499.84


  • dementia
  • risk factors
  • primary care
  • collaboration
  • healthy ageing