High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules

  • Bottomley, Stephen (Primary Chief Investigator (PCI))
  • Hoogenraad, Nicholas (Chief Investigator (CI))
  • Howlett, Geoffrey John (Chief Investigator (CI))
  • Klonis, Nectarios (Chief Investigator (CI))
  • Mulvaney, Paul (Chief Investigator (CI))
  • Perugini, Matthew (Chief Investigator (CI))
  • Ryan, Michael T. (Chief Investigator (CI))
  • Whisstock, James (Chief Investigator (CI))

Project: Research

Project Details

Project Description

This request is for an analytical ultracentrifuge with sensitive scanning optics to measure the size and interactions of complexes formed by proteins and other biomolecules. This high-speed ultracentrifuge facility will allow sedimentation rates in high gravitational fields to be monitored as a means of characterizing the low-abundance macromolecular assemblies that exist in living cells. The facility will be used in high-throughput drug screening and in the characterization of new biomaterials. This equipment, the first for Australia, will stimulate cutting-edge research projects in biotechnology and nanotechnology, support Australian industry and provide new training opportunities for post-doctoral and post-graduate students.
Effective start/end date1/01/0531/12/05


  • Australian Research Council (ARC)
  • Monash University
  • Monash University