High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules

  • Bottomley, Stephen, (Primary Chief Investigator (PCI))
  • Hoogenraad, Nicholas (Chief Investigator (CI))
  • Howlett, Geoffrey John (Chief Investigator (CI))
  • Klonis, Nectarios (Chief Investigator (CI))
  • Mulvaney, Paul (Chief Investigator (CI))
  • Perugini, Matthew (Chief Investigator (CI))
  • Ryan, Michael T. (Chief Investigator (CI))
  • Whisstock, James (Chief Investigator (CI))

Project: Research

Project Description

This request is for an analytical ultracentrifuge with sensitive scanning optics to measure the size and interactions of complexes formed by proteins and other biomolecules. This high-speed ultracentrifuge facility will allow sedimentation rates in high gravitational fields to be monitored as a means of characterizing the low-abundance macromolecular assemblies that exist in living cells. The facility will be used in high-throughput drug screening and in the characterization of new biomaterials. This equipment, the first for Australia, will stimulate cutting-edge research projects in biotechnology and nanotechnology, support Australian industry and provide new training opportunities for post-doctoral and post-graduate students.
Effective start/end date1/01/0531/12/05


  • Australian Research Council (ARC)
  • Monash University
  • Monash University