High resolution structural determination of pathogenic flaviviruses by cryo-EM using a chimeric platform

Watterson, Daniel (Primary Chief Investigator (PCI))
Hobson-Peters, Jody (Chief Investigator (CI))
Coulibaly, Fasseli (Chief Investigator (CI))
Hall, Roy (Chief Investigator (CI))
Young, Paul R. (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/19 → 31/12/21

2 Article

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses
Hardy, J. M., Newton, N. D., Modhiran, N., Scott, C. A. P., Venugopal, H., Vet, L. J., Young, P. R., Hall, R. A., Hobson-Peters, J., Coulibaly, F. & Watterson, D., Dec 2021, In: Nature Communications. 12, 1, 13 p., 3266.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

28 Citations (Scopus)
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Newton, N. D., Hardy, J. M., Modhiran, N., Hugo, L. E., Amarilla, A. A., Bibby, S., Venugopal, H., Harrison, J. J., Traves, R. J., Hall, R. A., Hobson-Peters, J., Coulibaly, F. & Watterson, D., 14 May 2021, In: Science Advances. 7, 20, 11 p., eabe4507.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

30 Citations (Scopus)

MASSIVE
Slava Kitaeff (Manager) & David Powell (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility
Ramaciotti Centre for Cryo-Electron Microscopy
Georg Ramm (Manager), Simon Andrew Crawford (Operator), Hariprasad Venugopal (Operator), Joan Marea Clark (Operator) & Gediminas Gervinskas (Operator)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility