Glioblastoma - inhibition of P2X7R as a potential therapeutic target for treatment of this aggressive cancer.

Project: Research

Status	Finished
Effective start/end date	1/01/22 → 31/12/25

Characterisation of the expression of P2X7 receptor, cancer stem cell markers and immunological mediators in human high-grade gliomas
Kan, L. K., Drill, M., Muscat, A., Sanfilippo, P., Sequeira, R. P., Jayakrishnan, P. C., Vo, A., Wong, N. C., Todaro, M., McLean, C., Drummond, K. J., Hunn, M., Williams, D. A., O’Brien, T. J. & Monif, M., Dec 2025, In: BMC Neuroscience. 26, 1, 15 p., 59.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
Harnessing the innate immune system for glioblastoma therapeutics
McLean, H., Drill, M., Sequeira, R., Jayakrishnan, P. C., Jeffree, R. L., Hunn, M., O'Brien, T. J., Hamilton, J. & Monif, M., 15 Oct 2025, In: Journal of Neuroimmunology. 407, 13 p., 578713.
Research output: Contribution to journal › Article › Research › peer-review

1 Link opens in a new tab Citation (Scopus)
Purinergic P2X receptor 7 (P2X7R) inhibition induced cytotoxicity in glioblastoma
Drill, M., Kan, L. K., Sequeira, R. P., Jayakrishnan, P. C., Hunn, M., Jones, N. C., O’Brien, T. J. & Monif, M., Sept 2025, In: PLoS ONE. 20, 9, 20 p., e0332212.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Link opens in a new tab Citation (Scopus)

FlowCore (FLOW)
Fryga, A. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Monash Micro Imaging (MMI)
Firth, S. (Manager), Fulcher, A. (Operator), Chernyavskiy, O. (Operator), Rzeszutek, M. (Other), Potter, D. (Manager), Hilsenstein, V. (Operator), Nunez-Iglesias, J. (Other), Cody, S. (Manager), Carmichael, I. (Operator), Kouskousis, B. (Other), Creed, S. (Manager) & Ballerin, G. (Operator)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility

Project Details