G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

Research output

Research output per year 2018 2022 2023 2024 2024

• 7 Review Article
• 3 Article

Research output per year

Research output per year

Search results

• 2024

  Targeting G protein-coupled receptors for heart failure treatment

  Thai, B. S., Chia, L. Y., Nguyen, A. T. N., Qin, C., Ritchie, R. H., Hutchinson, D. S., Kompa, A., White, P. J. & May, L. T., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2270-2286 17 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• The role of the adenosine system in epilepsy and its comorbidities

  Baltos, J. A., Casillas-Espinosa, P. M., Rollo, B., Gregory, K. J., White, P. J., Christopoulos, A., Kwan, P., O'Brien, T. J. & May, L. T., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2143-2157 15 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  11 Citations (Scopus)
• 2023

  Small molecule allosteric modulation of the adenosine A₁ receptor

  Nguyen, A. T. N., Tran, Q. L., Baltos, J. A., McNeill, S. M., Nguyen, D. T. N. & May, L. T., 26 Jun 2023, In: Frontiers in Endocrinology. 14, 12 p., 1184360.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  6 Citations (Scopus)

• The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors

  Zhang, L., Mobbs, J. I., May, L. T., Glukhova, A. & Thal, D. M., Apr 2023, In: Current Opinion in Structural Biology. 79, 9 p., 102560.

  Research output: Contribution to journal › Review Article › Research › peer-review
  7 Citations (Scopus)
• 2022

  Adenosine receptor signalling in Alzheimer’s disease

  Trinh, P. N. H., Baltos, J. A., Hellyer, S. D., May, L. T. & Gregory, K. J., Jul 2022, In: Purinergic Signalling. 18, p. 359–381 23 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  11 Citations (Scopus)

• Examining the Role of the Linker in Bitopic N⁶-Substituted Adenosine Derivatives Acting as Biased Adenosine A₁Receptor Agonists

  Awalt, J. K., Nguyen, A. T. N., Fyfe, T. J., Thai, B. S., White, P. J., Christopoulos, A., Jörg, M., May, L. T. & Scammells, P. J., 21 Jun 2022, In: Journal of Medicinal Chemistry. 65, 13, p. 9076–9095 20 p.

  Research output: Contribution to journal › Article › Research › peer-review
  1 Citation (Scopus)

• Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35

  Qin, C. X., Norling, L. V., Vecchio, E. A., Brennan, E. P., May, L. T., Wootten, D., Godson, C., Perretti, M. & Ritchie, R. H., Oct 2022, In: British Journal of Pharmacology. 179, 19, p. 4617-4639 23 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  25 Citations (Scopus)

• Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

  May, L. T., Bartolo, B. A., Harrison, D. G., Guzik, T., Drummond, G. R., Figtree, G. A., Ritchie, R. H., Rye, K. A. & de Haan, J. B., 9 Dec 2022, In: Clinical Science. 136, 23, p. 1731-1758 28 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
  4 Citations (Scopus)
• 2019

  Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology

  Sengmany, K., Hellyer, S. D., Albold, S., Wang, T., Conn, P. J., May, L. T., Christopoulos, A., Leach, K. & Gregory, K. J., 1 May 2019, In: Neuropharmacology. 149, p. 83-96 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  16 Citations (Scopus)
• 2018

  Structure of the adenosine-bound human adenosine A₁ receptor-G_i complex

  Draper-Joyce, C. J., Khoshouei, M., Thal, D. M., Liang, Y. L., Nguyen, A. T. N., Furness, S. G. B., Venugopal, H., Baltos, J. A., Plitzko, J. M., Danev, R., Baumeister, W., May, L. T., Wootten, D., Sexton, P. M., Glukhova, A. & Christopoulos, A., 20 Jun 2018, In: Nature. 558, 7711, p. 559-565 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  243 Citations (Scopus)