G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

Project: Research

Status	Active
Effective start/end date	1/01/18 → 30/06/23

Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology
Sengmany, K., Hellyer, S. D., Albold, S., Wang, T., Conn, P. J., May, L. T., Christopoulos, A., Leach, K. & Gregory, K. J., 1 May 2019, In: Neuropharmacology. 149, p. 83-96 14 p.
Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)
Structure of the adenosine-bound human adenosine A₁ receptor-G_i complex
Draper-Joyce, C. J., Khoshouei, M., Thal, D. M., Liang, Y. L., Nguyen, A. T. N., Furness, S. G. B., Venugopal, H., Baltos, J. A., Plitzko, J. M., Danev, R., Baumeister, W., May, L. T., Wootten, D., Sexton, P. M., Glukhova, A. & Christopoulos, A., 20 Jun 2018, In: Nature. 558, 7711, p. 559-565 7 p.
Research output: Contribution to journal › Article › Research › peer-review

178 Citations (Scopus)

Project Details