Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/20 → 31/12/22 |
Funding
- NHMRC - National Health and Medical Research Council (Australia): A$581,520.00
Keywords
- influenza
- inflammation
- innate immunity
- host/pathogen interaction
- virus pathogenesis
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NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis
Lam, M., Barry, K. T., Hodges, C. J., Harpur, C. M., Ong, J. D. H., Rosli, S., West, A. C., Dousha, L., Hertzog, P. J., Mansell, A. & Tate, M. D., 21 Mar 2025, In: Respiratory Research. 26, 1, 17 p., 109.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
Toward targeted treatments for silicosis
Barnes, H., Lam, M., Tate, M. D. & Hoy, R., Mar 2024, In: Current Opinion in Pulmonary Medicine. 30, 2, p. 185-194 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
9 Link opens in a new tab Citations (Scopus) -
Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation
Barry, K., Harpur, C., Lam, M., Tate, M. D. & Mansell, A., 10 Nov 2023, In: Journal of Inflammation. 20, 1, 12 p., 38.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus)
-
Targeting pyroptosis to limit the severity of influenza virus infections
Tate, M. (Primary Chief Investigator (PCI)), Lawlor, K. (Associate Investigator (AI)), Mansell, A. (Associate Investigator (AI)) & Hertzog, P. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Potential of the NLRP3 inflammasome as a biomarker and therapeutic target in silicosis
Tate, M. (Primary Chief Investigator (PCI)) & Mansell, A. (Chief Investigator (CI))
Department of Health, Disability and Ageing (Australia)
1/08/21 → 31/07/24
Project: Research
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Understanding and modulating hyperinflammation caused by influenza viruses
Tate, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/17 → 30/09/21
Project: Research
Equipment
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FlowCore (FLOW)
Fryga, A. (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility
-
Monash Animal Research Platform (MARP)
Findlay, C. (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility
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Monash Micro Imaging (MMI)
Firth, S. (Manager), Fulcher, A. (Operator), Chernyavskiy, O. (Operator), Rzeszutek, M. (Other), Potter, D. (Manager), Hilsenstein, V. (Operator), Nunez-Iglesias, J. (Other), Cody, S. (Manager), Carmichael, I. (Operator), Kouskousis, B. (Other), Creed, S. (Manager) & Ballerin, G. (Operator)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility