Fibroblast Senescence as a driver of pulmonary fibrosis

Knight, Darryl (Primary Chief Investigator (PCI))
Burgess, Janette Kay (Chief Investigator (CI))
Westall, Glen (Chief Investigator (CI))
Laurent, Geoffrey (Chief Investigator (CI))

Medicine Alfred Hospital

Project: Research

Status	Finished
Effective start/end date	1/01/16 → 31/12/19

3 Article
1 Review Article

Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner
Schuliga, M., Read, J., Blokland, K. E. C., Waters, D. W., Burgess, J., Prêle, C., Mutsaers, S. E., Jaffar, J., Westall, G., Reid, A., James, A., Grainge, C. & Knight, D. A., Apr 2020, In: Clinical Science. 134, 7, p. 889-905 17 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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19 Citations (Scopus)
Senescence of ipf lung fibroblasts disrupt alveolar epithelial cell proliferation and promote migration in wound healing
Blokland, K. E. C., Waters, D. W., Schuliga, M., Read, J., Pouwels, S. D., Grainge, C. L., Jaffar, J., Westall, G., Mutsaers, S. E., Prêle, C. M., Burgess, J. K. & Knight, D. A., Apr 2020, In: Pharmaceutics. 12, 4, 11 p., 389.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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16 Citations (Scopus)
STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts
Waters, D. W., Blokland, K. E. C., Pathinayake, P. S., Wei, L., Schuliga, M., Jaffar, J., Westall, G. P., Hansbro, P. M., Prele, C. M., Mutsaers, S. E., Bartlett, N. W., Burgess, J. K., Grainge, C. L. & Knight, D. A., Jan 2019, In: American Journal of Respiratory Cell and Molecular Biology. 61, 1, p. 61-73 13 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
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40 Citations (Scopus)